The 1% XG gel with high Mw (6.9 × 10⁶ Da) was more effective for the prevention of adhesions compared to a commercially available gel (1.2% sodium hyaluronate).
For XG with Mw of 5.5 × 10⁶ Da, a 1% or greater concentration was needed to form a gel with required effect as an anti-adhesion agent. The results showed that XG exerts an anti-adhesion effect in the rat abdominal cavity. molecular weight (Mw) (2.5 × 10⁶ Da–6.9 × 10⁶ Da) were prepared to estimate their potential application as an injectable tissue adhesion barrier. In this study, XG with different concentrations (0.5%–2%, w/v) and. Therefore, it is still crucial to develop new products that are effective in a variety of surgical applications. Polymer barriers are widely used to prevent adhesions, although none have been able to completely prevent adhesions in all situations. Postoperative adhesions remain a significant concern following abdominal surgery.
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